Take the Eastern Freeway (M3) then the Maroondah Highway (B360) through Healesville, then continue north via Yarra Glen and Alexandra.
Take the Metropolitan Ring Road (M80) east to the Eastern Freeway, then follow the Maroondah Highway route through to Alexandra and Eildon.
Take the Ring Road around Melbourne or through the CBD, then follow the Eastern Freeway route north-east into lake country.
Head south via Nagambie and Seymour, then east through Yea to Alexandra and Eildon — or via Mansfield for the High Country approach.
Healesville for a coffee and the bakeries, Yarra Glen for the wineries and valley views, then Alexandra — the last major town for a supermarket, fuel and cafes — as you drop into lake country.
Via Yea for a flatter, caravan-friendly run, a scenic detour through Marysville past Steavenson Falls, or in from the east via Mansfield near Mt Buller.
There is no public transport to Lake Eildon — a car is essential. Car hire is available at Melbourne Airport and throughout the city. Consider a 4WD if you plan to explore remote areas or bush camping spots.